Anticaries Activity of Usnea pictoides G. Awasthi -A macrolichen from Western Ghats of Karnataka, India

Autor:	N Dileep, Syed Junaid, KN Rakesh, Ktr Prashith, KS Vinayaka
Rok vydání:	2014
Předmět:	Usnea Chloroform biology Traditional medicine Usnic acid Ethyl acetate biology.organism_classification Streptococcus mutans Industrial and Manufacturing Engineering Solvent chemistry.chemical_compound chemistry Parmeliaceae Botany Petroleum ether
Zdroj:	Science, Technology and Arts Research Journal. 2:87
ISSN:	2305-3372 2226-7522
DOI:	10.4314/star.v2i4.14
Popis:	The present study was conducted to determine anticaries activity of solvent extracts of a macrolichen Usnea pictoides G. Awasthi (Parmeliaceae) collected at Mullayanagiri, Western Ghats of Chikmagalur district, Karnataka, India. The lichen material was sequentially extracted using solvents viz., petroleum ether, ethyl acetate, chloroform and methanol in a soxhlet assembly. Anticaries activity of solvent extracts was determined against four clinical isolates of Streptococcus mutans (recovered from dental caries subjects) by Agar well diffusion assay. All solvent extracts were effective against the clinical isolates. High inhibitory potential was observed in case of chloroform extract. Thin layer chromatogram showed the presence of Usnic acid. Inhibitory effect could be ascribed to the bioactive secondary metabolites, mainly Usnic acid present in the lichen. Purification of bioactive principles and determination of their anticaries activity are to be conducted.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7438d5e37bfbdab34a60620c048a3c0f https://doi.org/10.4314/star.v2i4.14 Zobrazit plný text záznamu