The RTS&T Code Coupled with the Microscopic Kinetic Model for Biological Calculations in Multi-Ion Therapy
| Autor: | M. A. Belikhin, A. A. Pryanichnikov, R. Yu. Sunyukov, I. I. Degtyarev, A. S. Simakov, F. N. Novoskoltsev, E. V. Altukhova, Yu. V. Altukhov |
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| Rok vydání: | 2020 |
| Předmět: |
Physics
Nuclear and High Energy Physics Radiation Proton Kinetic model 010308 nuclear & particles physics Carbon ion beam 01 natural sciences Atomic and Molecular Physics and Optics Computational physics Ion Homogeneous 0103 physical sciences Code (cryptography) Radiology Nuclear Medicine and imaging Irradiation 010306 general physics |
| Zdroj: | Physics of Particles and Nuclei Letters. 17:629-634 |
| ISSN: | 1531-8567 1547-4771 |
| DOI: | 10.1134/s1547477120040378 |
| Popis: | The exact calculation of the delivered dose in the process of irradiating tumors with proton and carbon ion beams is one of the most important components of the process of planning radiation therapy. Today there are two advanced microdosimetric models for calculation the relative biological efficacy of radiation, that are used in clinical practice. This is Microdosimetric Kinetic Model (MKM) and Local Effect Model (LEM). This paper contains descriptions of the features of the implementation of the MKM as model that is included in the RTS&T code system. The results of theoretical and experimental studies of the main microdosimetric characteristics for cellular structures placed in homogeneous water phantoms irradiated with 454 MeV/u 12C6+ ions are presented. |
| Databáze: | OpenAIRE |
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