ChemInform Abstract: Studies on the Synthesis of Benzimidazo[2,1-a]isoquinolines

Autor:	Paul Loria, Thomas Rodemann, Leslie W. Deady
Rok vydání:	2010
Předmět:	chemistry.chemical_classification Isocoumarin chemistry.chemical_compound chemistry Nitration Amide Electrophile Organic chemistry General Medicine Isoquinoline Aldehyde Derivative (chemistry)
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199907160
Popis:	The reaction of the isocoumarin derivative 1-acetylimino-3-methyl-1H-2-benzopyran-4-carbonitrile (1a) with aromatic ortho diamines provides entry to the benzimidazo[2,1-a]isoquinoline and related systems. Various conversions of the methyl and cyano groups in the tetracycles into amide, aldehyde and acid functions have been carried out, along with studies of electrophilic nitration.
Databáze:	OpenAIRE
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