Concentrations of elements in brain tumours

Autor:	Henning Scheibler, László Bezúr, E. Andrási, László Ernyei, László Orosz
Rok vydání:	1995
Předmět:	Chemistry Inductively coupled plasma atomic emission spectroscopy Radiochemistry Analytical chemistry medicine Neutron activation analysis Inductively coupled plasma medicine.disease Optical emission spectrometry Analytical Chemistry Atomic emission spectrometry Glioblastoma
Zdroj:	Mikrochimica Acta. 118:113-121
ISSN:	1436-5073 0026-3672
DOI:	10.1007/bf01242234
Popis:	The aim of our experiments was to investigate the possible elemental concentration changes in brain tumours (glioblastoma multiforme). Our project also incorporated the determination of the regional distribution of elements in normal human brains. 17 elements (Na, K, Ca, Mg, Fe, P, S, Al, B, Ba, Co, Cr, Ni, Mn, Pb, Sr, Zn) have been measured in 21 different regions of 20 normal brains and in clinically and histopathologically selected brain regions of patients with brain tumours. Analyses were carried out by instrumental neutron activation analysis (INAA) and inductively coupled plasma atomic emission spectrometry (ICP-AES). Quality control was ensured by using NBS Bovine Liver 1577a standard reference material. Comparison between the healthy and brain tumour concentration data using statistical evaluation revealed only a few elements (e.g. B, Zn, Sr) which showed significant differences as a consequence of the brain tumour.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::73fa1498464fd1c0c1e7f811a9a44c9f https://doi.org/10.1007/bf01242234 Zobrazit plný text záznamu Full text from SpringerLink