Association between metabolic syndrome and gestational diabetes mellitus in women and their children: a systematic review and meta-analysis
| Autor: | Margaret Arstall, Maleesa M. Pathirana, Claire T. Roberts, Anna Ali, Prabha H. Andraweera, Zohra S Lassi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pregnancy
medicine.medical_specialty endocrine system diseases business.industry Offspring Obstetrics Endocrinology Diabetes and Metabolism nutritional and metabolic diseases 030209 endocrinology & metabolism Subgroup analysis medicine.disease female genital diseases and pregnancy complications Childhood obesity Gestational diabetes 03 medical and health sciences 0302 clinical medicine Endocrinology 030220 oncology & carcinogenesis Meta-analysis Diabetes mellitus medicine Metabolic syndrome business |
| Zdroj: | Endocrine. 71:310-320 |
| ISSN: | 1559-0100 1355-008X |
| DOI: | 10.1007/s12020-020-02492-1 |
| Popis: | The primary aim of this systematic review and meta-analysis was to determine the association between gestational diabetes mellitus (GDM) and metabolic syndrome (MetS) in women and children. Our secondary aim was to assess the development of MetS with respect to the elapsed time postpartum at which MetS was diagnosed. This review is registered with PROSPERO (CRD42020173319). PubMed, CINHAL, SCOPUS, and EMBASE databases were searched. Studies reporting on the rate of MetS in pregnant women with GDM, the rate of MetS in women with a history of GDM, and the rate of MetS in offspring exposed to GDM in utero compared to healthy controls were selected. We identified 588 articles from the literature search. Fifty-one studies were included in the review and of those 35 were included in the meta-analysis. Quantitative summary measures showed that women with a history of GDM had an increased risk of developing MetS compared to those without a history of GDM (RR 2.36, 95% CI 1.77–3.14, 29 studies, 13,390 participants; heterogeneity: χ2 p |
| Databáze: | OpenAIRE |
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