Regioselective electrophilic cyclization of o-ethynylbenzyl phenyl selenides to (Z)-1-methylidene-2-phenyl-1,3-dihydro-1H-benzo[c]selenophenium salts

Autor:	Shoko Nakabayashi, Haruki Sashida, Mamoru Kaname, Hirokazu Suzuki, Mao Minoura
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry Stereochemistry Organic Chemistry Drug Discovery Electrophile Regioselectivity Salt (chemistry) Biochemistry Medicinal chemistry Single crystal Derivative (chemistry)
Zdroj:	Tetrahedron Letters. 51:5395-5398
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2010.07.160
Popis:	o-Ethynylbenzyl phenyl selenides regioselectively reacted with trifluoromethanesulfonic acid to afford the (Z)-1-methylidene-2-phenyl-1,3-dihydro-1H-benzo[c]selenophenium salts as the major products during the 5-exo-dig mode cyclization in good yields together with minor E isomers. The structure of the major (Z)-selenophenium salt was established by the single crystal X-ray crystallographic analysis using a tert-butyl derivative.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::73ec46e297efdc2402f3094ad94e04cd https://doi.org/10.1016/j.tetlet.2010.07.160 Zobrazit plný text záznamu Full Text from ScienceDirect