Effects of Autoprothrombin II-A on Epinephrine-Induced Platelet Aggregation of Normal- and Coumadin-Treated Dogs

Autor:	Walter H. Seegers, Gilbert E. Herman, Raymond L. Henry
Rok vydání:	1978
Předmět:	High concentration medicine.medical_specialty Platelet aggregation Chemistry Hematology Endocrinology Epinephrine Autoprothrombin II Induced platelet aggregation Internal medicine medicine Platelet Protein C medicine.drug Factor IX
Zdroj:	Thrombosis and Haemostasis. 40:061-065
ISSN:	2567-689X 0340-6245
DOI:	10.1055/s-0038-1648634
Popis:	SummaryPlatelet-rich plasma from dogs and from coumadin-treated dogs aggregated at the same optimum concentration of epinephrine. Neither protein C nor its active form called autoprothrombin II-A was necessary for aggregation of dog platelets with epinephrine. For platelet aggregation, suboptimal concentrations of epinephrine were potentiated by addition of purified autoprothrombin II-A. The latter, by itself, induced platelet aggregation in high concentration.
Databáze:	OpenAIRE
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