Outpatient Use of Monoclonal Antibodies Casirivimab and Imdevimab in Pregnancy for Mild-to-Moderate Coronavirus Disease 2019

Autor:	Antonio Riccardo Buonomo, Isabella Di Filippo, Nunzia Esposito, Gabriele Saccone, Mariano Nobile, Giulio Viceconte, Riccardo Villari, Costantino Di Carlo, Giuseppe Bifulco, Ivan Gentile
Rok vydání:	2023
Předmět:	Pediatrics Perinatology and Child Health Obstetrics and Gynecology
Zdroj:	American Journal of Perinatology.
ISSN:	1098-8785 0735-1631
Popis:	Objective The aim of this study was to report the use casirivimab/imdevimab therapy in pregnant women with moderate coronavirus disease 2019 (COVID-19). Study Design We report 12 cases of unvaccinated pregnant patients with mild-to-moderate COVID-19 treated with casirivimab/imdevimab. Results Twelve unvaccinated pregnant patients with mild-to-moderate COVID-19 received casirivimab/imdevimab at the dose of 1200/1200 mg by intravenous infusion over 60 minutes. All women were managed outpatient. None experienced severe adverse drug reaction and none progressed to severe disease. Conclusion Casirivimab/imdevimab should be considered for outpatient treatment of unvaccinated pregnant women with mild-to-moderate COVID-19 to decrease the risk of severe disease. Key Points
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::73ca37518eb53095df354cc75141bf6f https://doi.org/10.1055/s-0042-1753488 Zobrazit plný text záznamu