Inactivation of myostatin by photooxygenation using functionalized d-peptides

Autor:	Hideyuki Okamoto, Shuko Amber Murano, Kaoru Ikekawa, Masahiro Katsuyama, Sho Konno, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi
Rok vydání:	2023
Předmět:	Pharmacology Organic Chemistry Drug Discovery Pharmaceutical Science Molecular Medicine Biochemistry
Zdroj:	RSC Medicinal Chemistry. 14:386-392
ISSN:	2632-8682
DOI:	10.1039/d2md00425a
Popis:	Myostatin-binding d-peptides functionalized with photocatalyst efficiently inactivate myostatin by photooxygenation and show no phototoxicity and high resistance to proteolytic enzymes, leading to the treatment of muscular atrophic diseases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::73c442d5b725c15e6bb798137ca3442e https://doi.org/10.1039/d2md00425a Zobrazit plný text záznamu