Does erythrocyte infusion improve 3.2-km run performance at high altitude?

Autor: M. W. Sharp, R. R. Cote, J L Kenney, Andrew J. Young, B J Freund, Michael N. Sawka, C. R. Valeri, Kent B. Pandolf
Rok vydání: 1998
Předmět:
Zdroj: European Journal of Applied Physiology. 79:1-6
ISSN: 1439-6327
1439-6319
DOI: 10.1007/s004210050465
Popis: The effects of autologous erythrocyte infusion on improving exercise performance at high altitude have not previously been studied. The effects of erythrocyte infusion on 3.2-km (2-mile) run performance were evaluated during 3 days (HA3) and 14 days (HA14) exposure to high altitude (4300 m) in erythrocyte-infused (ER) and control (CON) subjects that were initially matched (P > 0.05; n = 8 in each group) for age, body size and aerobic fitness. After sea-level runs (SL; 50 m), unacclimated-male subjects received either 700 ml of saline and autologous erythrocytes (42% hematocrit; ER) or saline alone (CON). The 3.2-km run times (min:s) did not differ (P > 0.05) between groups at SL [mean (SEM) ER, 13:14 (00:19); CON, 13:39 (00:32)] or during HA3 [ER, 19:02 (00:18); CON, 19:44 (00:43)] and HA14 [ER, 17:44 (00:27); CON, 18:45 (00:55)] but times were slower (P 0.05) for ER compared to CON. Thus, no significant improvements in 3.2-km run performance were associated with erythrocyte infusion, although the ER group showed a tendency to run slightly faster at high altitude.
Databáze: OpenAIRE