Lebensqualität und Therapieerfolg in der ambulanten Schizophrenie-Therapie mit Flupentixol: Eine Anwendungsbeobachtung

Autor:	H. Landen, M. Thiel, B. B. Quednow, Kühn Ku, M. Riedel
Rok vydání:	2004
Předmět:	medicine.medical_specialty Surveillance study business.industry Flupenthixol medicine.disease Psychiatry and Mental health Neurology Tolerability Schizophrenia Concomitant Physical therapy Medicine Observational study Neurology (clinical) business Psychiatry Adverse effect
Zdroj:	Fortschritte der Neurologie · Psychiatrie. 72:397-403
ISSN:	1439-3522 0720-4299
DOI:	10.1055/s-2004-818386
Popis:	The objective of this phase IV surveillance study was to document the efficacy and tolerability of flupenthixol as well as the quality of life of patients suffering from schizophrenia and to gain insights into which doses were actually used in specialists outpatients care. The observational variables in this study include demographic variables, details of the diagnosis as well as concomitant diseases. Further evaluations included the assessment of CGI-Scale and subjective patient quality of live assessment using a standardised questionnaire. This questionnaire SWN-K (subjective well-being under neuroleptic treatment; short version) includes 20 items on the state of health with a six-point scale from "absolutely not" to "very strong" respectively. 66.3 % Patients were treated with the depot form of flupenthixol, the rest with oral medication with mean doses of 9.2 mg/d i. m. and 6.3 mg/d p. o. respectively. 78.8 % of patients improved on the CGI-Scale, 5.5 % had an adverse event and in 4.6 % of patients this event was related to the medication. 0.3 % of patients had a serious adverse event. The mean of SWN-K improved from 61.2 to 78.5 in the course of study. The CGI improved from 5.83 to 3.43 in the course of treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::73aef4e06936c9c78aa14553352b908e https://doi.org/10.1055/s-2004-818386 Zobrazit plný text záznamu