| Autor: |
Bryden Wa, McLoughlin M, Dapeng Chen, Caton Er, Devin Ap |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.1101/2021.06.05.447210 |
| Popis: |
Aerosols contain human pathogens that cause public health disasters such as tuberculosis (TB) and the ongoing COVID-19 pandemic. The current technologies for the collection of viruses and microorganisms in aerosols face critical limitations, necessitating the development of a new type of sampling system to advance the capture technology. Herein, we presented a new type of collection system, which exploits the affinity between carbon chains and organic molecules on the surfaces of viruses and microorganisms. We demonstrated that the physical capture efficiency of the collection system was over 99% for particle sizes from 0.3 to 10 µm. We further evaluated the biochemical capture efficiency of the collection system using mass spectrometry approaches and showed that the biochemical information of viruses and microorganisms was well preserved. Coupled with well-established molecular technologies, this new type of capture technology can be used for the investigation of aerosol-related disease transmission models, as well as the development of innovative screening and monitoring tools for human diseases and public health issues. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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