Detection of Early Myocardial Injury in Children with Ventricular Septal Defect Using Cardiac Troponin I and Two-Dimensional Speckle Tracking Echocardiography
| Autor: | Alyaa A. Kotby, Marwa M. Al-Fahham, Manal M. Abd Al Aziz, Adel H Husseiny |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Cardiac troponin business.industry Hemodynamics Speckle tracking echocardiography 030204 cardiovascular system & hematology Vascular surgery medicine.disease Asymptomatic Cardiac surgery 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Internal medicine Heart failure Pediatrics Perinatology and Child Health Troponin I cardiovascular system Cardiology Medicine medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Pediatric Cardiology. 41:1548-1558 |
| ISSN: | 1432-1971 0172-0643 |
| Popis: | Children with ventricular septal defects (VSDs) are subjected to hemodynamic overload which causes myocardial injury and subsequent heart failure. Early stages of myocardial damage cannot be detected by conventional echocardiography. Two-dimensional speckle tracking echocardiography (2D-STE) and cardiac troponin I (cTnI) have been recently introduced as more accurate tools for early assessment of cardiovascular diseases. The purpose of this study is to evaluate the role of cardiac troponin I (cTnI) and 2D-STE in the early detection of VSD-induced myocardial injury. Thirty children with VSD (symptomatic and asymptomatic) and 30 controls were assessed serologically by measuring serum cTnI and by conventional echocardiography. STE was performed to measure the averaged global peak longitudinal systolic stain [G peak SL(AVG)]. Serum cTnI levels were significantly higher in patients when compared to controls (P |
| Databáze: | OpenAIRE |
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