Ektopische Choriongonadotropinbildung in Apudomen
| Autor: | Scherbaum W, P Sadowski, F Heni, F J Seif, Kruz-Isler G |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
endocrine system
medicine.medical_specialty medicine.drug_class Chemistry Intestinal Neoplasm Vasoactive intestinal peptide Ileum General Medicine medicine.disease Apudoma Pheochromocytoma medicine.anatomical_structure Endocrinology Internal medicine medicine Pancreatic Vipoma Carcinoid tumour Gonadotropin |
| Zdroj: | DMW - Deutsche Medizinische Wochenschrift. 103:253-259 |
| ISSN: | 1439-4413 0012-0472 |
| DOI: | 10.1055/s-0028-1104417 |
| Popis: | Two pheochromocytomas, two carcinoid tumours of the ileum and one pancreatic vipoma showed APUD-system properties and formed electron-dense secretory granules indicating synthesis and storage of proteohormones. Besides catecholamines, 5-hydroxytryptamine and vasoactive intestinal polypeptide, all five tumours contained immunoreactive chorionic gonadotropin and also its free, protomeric beta chain as a sign of de-differentiation. Plasma of the tumour patients also contained immunoreactive chorionic gonadotropin and the free protomeric beta chain, both of which are useful tumour markers. |
| Databáze: | OpenAIRE |
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