Maladie de Basedow chez un adolescent porteur d'une histiocytose X

Autor:	M Polak, MC Commare-Nordmann, L Viollet, J Langlais, J Donadieu
Rok vydání:	1997
Předmět:	Autoimmune disease Pathology medicine.medical_specialty business.industry Graves' disease Autoantibody medicine.disease Pathogenesis Histiocytosis Carbimazole Langerhans cell histiocytosis Immunopathology Pediatrics Perinatology and Child Health Medicine business medicine.drug
Zdroj:	Archives de Pédiatrie. 4:656-658
ISSN:	0929-693X
DOI:	10.1016/s0929-693x(97)83368-4
Popis:	Background. - Immunological dysfunction is known to be present in Langerhans cell histiocytosis: some autoimmune diseases with autoantibodies associated with this condition have already been described. This immunological dysfunction could play a role in the Langerhans cell histiocytosis pathogenesis. Case report. - A 13 year-old boy presented a multifocal bone Langerhans cell histiocytosis associated with Graves' syndrome. This last condition was successfully treated with carbimazole while the focal lesions of histiocytosis did not require any treatment. Conclusion. - This unique association could be explained by the immunological dysfunction seen in Langerhans cell histiocytosis with secondary appearance of thyreo-stimulating antibodies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::736ff6d49c19d203f7e292447ce1a4c0 https://doi.org/10.1016/s0929-693x(97)83368-4 Zobrazit plný text záznamu Full Text from ScienceDirect