Enantioselective synthesis of nagilactone F via vinylsilane-terminated cationic cyclization

Autor:	Steven D. Burke, Louis A. Silks, Sharon M.S. Strickland, Kort Michael E, Helen M. Organ
Rok vydání:	1994
Předmět:	Intramolecular reaction Chemistry Stereochemistry Organic Chemistry Cationic polymerization Enantioselective synthesis Total synthesis Polyene Biochemistry chemistry.chemical_compound Intramolecular force Drug Discovery Alkoxy group Vinylsilane
Zdroj:	Tetrahedron Letters. 35:1503-1506
ISSN:	0040-4039
Popis:	An enantioselective total synthesis of nagilactone F is described. Functionalized tricyclic intermediate 3 was prepared using a high-yielding acetal-initiated/vinylsilane-terminated polyene cyclization of 5. Intramolecular alkoxy radical-mediated remote functionalization established the D-ring of the nagilactone system.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::735979640ad26693ac433af49d16f7ae https://doi.org/10.1016/s0040-4039(00)76743-8 Zobrazit plný text záznamu