Comparison of enantiomer separation by inclusion chromatography and by resolution via diastereoisomeric salt formation

Autor: Gy. Pokol, B. Zsadon, Cs. Novák, M. Acs, Elemér Fogassy, Ferenc Faigl, A. Ujházy
Rok vydání: 1987
Předmět:
Zdroj: Reactive Polymers, Ion Exchangers, Sorbents. 6:197-202
ISSN: 0167-6989
DOI: 10.1016/0167-6989(87)90089-4
Popis: Enantiomers of 6,7-dihydroxy-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride were separated via diastereoisomeric salt formation using optically active tartaric acid, by inclusion-complex formation using water-soluble cyclodextrin polymer, and by inclusion chromatography on β-cyclodextrin bead polymer. On a microscale, the chromatographic resolution has significant advantages over the traditional methods.
Databáze: OpenAIRE