Comparison of enantiomer separation by inclusion chromatography and by resolution via diastereoisomeric salt formation
Autor: | Gy. Pokol, B. Zsadon, Cs. Novák, M. Acs, Elemér Fogassy, Ferenc Faigl, A. Ujházy |
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Rok vydání: | 1987 |
Předmět: | |
Zdroj: | Reactive Polymers, Ion Exchangers, Sorbents. 6:197-202 |
ISSN: | 0167-6989 |
DOI: | 10.1016/0167-6989(87)90089-4 |
Popis: | Enantiomers of 6,7-dihydroxy-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride were separated via diastereoisomeric salt formation using optically active tartaric acid, by inclusion-complex formation using water-soluble cyclodextrin polymer, and by inclusion chromatography on β-cyclodextrin bead polymer. On a microscale, the chromatographic resolution has significant advantages over the traditional methods. |
Databáze: | OpenAIRE |
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