COMPARISON OF α –GLUCOSIDASE INHIBITORY ACTIVITY OF Moringa oleifera ETHANOLIC EXTRACT
| Autor: | Rizky Rahmwaty Alami, Yulia Yusrini Djabir, Herlina Rante |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Ethanol
General Veterinary Traditional medicine Glucosidase Inhibitor Positive control General Biochemistry Genetics and Molecular Biology Moringa chemistry.chemical_compound chemistry Maceration (wine) medicine General Agricultural and Biological Sciences Enzyme inhibitory α glucosidase inhibitory Acarbose medicine.drug |
| Zdroj: | Journal of Experimental Biology and Agricultural Sciences. 9:S269-S273 |
| ISSN: | 2320-8694 |
| Popis: | The purpose of this research was to determine the α-glucosidase enzyme inhibitory activity of Moringa oleifera plant samples collected from the three geographical areas viz., Saragi, Bacuhau, and Batumatongka of Southeast Sulawesi Indonesia. Ethanol extract of Moringa leaves was prepared by the maceration method using 95% ethanol. The estimation of α –glucosidase inhibitory activity of this extract was performed in vitro. The results of the study showed that ethanolic extract of three Moringa samples i.e. Sarangi, Bacuhau, and Batumatongka had the IC50value of 18.62, 10.18, 10.58 ppm, respectively while IC50value for the acarbose positive control was reported 11.54ppm. From the results of this study, it can be concluded that ethanolic extract of Moringa could inhibit α –glucosidase and this potential was similar to the commercial α –glucosidase inhibitor acarbose. |
| Databáze: | OpenAIRE |
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