Synthesis Biological Evaluation and Theoretical Sudies of 2-(2,4-Dimethoxyphenyl)-4,5-Dihydro-1h-Imidazole Derevatives

Autor:	Hanaa A. Altameemi, Firyal W. Askar, Olfat A. Nief, Barakat A. F. Kamel
Rok vydání:	2020
Předmět:	History biology Biological activity Imidazoline derivatives Antimicrobial biology.organism_classification Medicinal chemistry Computer Science Applications Education chemistry.chemical_compound chemistry Imidazole Bacteria Gram Biological evaluation
Zdroj:	Journal of Physics: Conference Series. 1664:012073
ISSN:	1742-6596 1742-6588
Popis:	The group of imidazoline derivatives is an important class of compounds that possess broad biological activity. Many derivatives that have been efficiently synthesized form 2-(-2,4-dimethoxyphenyl)-4,5dihydro-1H-imidazole as starting material to Synthesis of some derivatives. The structures were characterized by FTIR and 1H-NMR spectra. All The synthesized compounds were evaluated for their antimicrobial activities against two kind of bacteria (gram +ve) [ S. aureus, S.epidermi dis] and (gram –ve) [E.coli, Klebsiel lla spp] as well as fungi [C.albica ns] using the micro dilution procedure and compared with amoxicillin activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::734016cc54442fb2bb13bf0cd89fb0e7 https://doi.org/10.1088/1742-6596/1664/1/012073 Zobrazit plný text záznamu