Haemostatic Activation before and after Surgery in Patients with and without Gastric Malignancy

Autor:	Bredahl C, Hans B Rahr, J F Larsen, Jensen Fs, Sørensen Jv, Nieuwenhuizen W
Rok vydání:	1994
Předmět:	medicine.medical_specialty biology business.industry Stomach Cancer Hematology Malignancy medicine.disease Fibrinogen Fibrin Surgery medicine.anatomical_structure Hemostasis medicine biology.protein Gastric malignancy In patient business medicine.drug
Zdroj:	Thrombosis and Haemostasis. 71:713-718
ISSN:	2567-689X 0340-6245
DOI:	10.1055/s-0038-1642510
Popis:	SummaryPre- and postoperative plasma levels of Prothrombin Fragment 1 + 2 (F1+2), Thrombin-antithrombin III complex (TAT), Fibrinopeptide A (FpA), Fibrin and Fibrinogen Degradation Products (FbDP, FgDP) and Soluble Fibrin (SF) were measured in 40 patients undergoing gastric surgery in order to compare patients operated for benign (n = 21) and malignant (n = 19) disease. Plasma levels of F1+2, TAT, FbDP and SF on the first postoperative day were significantly higher than before operation. F1+2 and FbDP levels were further increased one week after surgery, at which time FgDP levels were also higher than preoperatively. A significant postoperative increase in FpA levels was found only in patients with malignant disease. When age was taken into consideration, significant differences between patients with and without malignancy were found only in the late postoperative period, as cancer patients had higher FpA and FbDP levels one week after surgery and higher FbDP levels one month after discharge from hospital.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::73251de4519244ff55795f4ce962d060 https://doi.org/10.1055/s-0038-1642510 Zobrazit plný text záznamu