A mild, general, and metal-free method for site-specific deuteration induced by visible light using D2O as the source of deuterium atoms

Autor:	Ruining Li, Zhankui Sun, Shuai Shi, Liangming Rao
Rok vydání:	2020
Předmět:	Steric effects chemistry.chemical_compound Materials science Deuterium chemistry Metal free Functional group Environmental Chemistry Substrate (chemistry) Photochemistry Pollution Sustainable energy Visible spectrum
Zdroj:	Green Chemistry. 22:669-672
ISSN:	1463-9270 1463-9262
DOI:	10.1039/c9gc04096j
Popis:	A radical deuteration procedure using D2O as the source of deuterium atoms is strongly preferred in terms of mildness, sustainability, and cost. Herein, we disclose a radical approach for site-specific, highly efficient and metal-free deuteration using D2O under visible light conditions. This desulfurization–deuteration strategy features mild conditions, broad substrate scope, highly efficient D-incorporation, excellent functional group compatibility, sustainable energy and is hardly affected by substrate steric factors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::73207500065a03bd71d394cee2bfae00 https://doi.org/10.1039/c9gc04096j Zobrazit plný text záznamu