Application of scoring system in FNAC of thyroid lesions

Autor:	Jyothi B Lingegowda, Ramkumar Kurpad Ramachandrarao, K Sathiyamurthy, Prakash H Muddegowda, M Shashikiran, Prasanna G. Konapur
Rok vydání:	2016
Předmět:	medicine.medical_specialty Pathology Multivariate analysis Scoring system Clinical pathology business.industry Thyroid Spearman's rank correlation coefficient Surgical pathology medicine.anatomical_structure Cytology medicine Histopathology business
Zdroj:	Indian Journal of Pathology and Oncology. 3:409
ISSN:	2394-6792 2394-6784
DOI:	10.5958/2394-6792.2016.00077.6
Popis:	Background: Assigning a score to cytology/FNA of thyroid lesions can provide important information regarding their neoplastic or non-neoplastic nature. The present study was undertaken to score thyroid lesions on aspirates based on various characteristics and correlating with standard cytological classification. Histopathology was done and the two cytological classification systems (Cytological scoring and Standard method) were compared. Methods: 196 cases of thyroid lesions with preoperative cytologic diagnosis were assigned cytological score/classified. Histopathology diagnosis was compared and statistical analysis was performed; correlation between cytologic score and histopathology was established using Spearman correlation coefficient. Regression analysis was done to assess the significance of each cytological score. Results: Multivariate analysis of cytologic features revealed that the amount of colloid, nuclear features and background pattern are the most influential features. There was high degree of correlation between the scoring methods on cytology with histopathology compared to standard cyto classification with histopathology. There was a significant association (p
Databáze:	OpenAIRE
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