Nachsorge des differenzierten Schilddrüsenkarzinoms unter spezieller Berücksichtigung des Serum-Thyreoglobulin-(hTg-)Spiegels
| Autor: | Pabst Hw, W. Kanitz, Böttger Ig, Heidenreich P, W. Dirr |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
endocrine system
Pathology medicine.medical_specialty endocrine system diseases Epithelioma business.industry medicine.medical_treatment Thyroid Thyroidectomy medicine.disease medicine.anatomical_structure Iodine uptake medicine Carcinoma Radiology Nuclear Medicine and imaging Thyroglobulin Papillary carcinoma business Hormone |
| Zdroj: | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 147:282-287 |
| ISSN: | 1438-9010 1438-9029 |
| DOI: | 10.1055/s-2008-1048640 |
| Popis: | The histories of 358 patients with carcinomas of the thyroid have been evaluated. Differentiated carcinomas of the thyroid (84.6%) were treated by means of thyroidectomy, ablative radio-iodine therapy (tissue dose 1000 Gray), TSH-suppressive thyroid hormone medication and, in special cases, external radiation. Even differentiated carcinomas showed a high recurrence rate. Metastases occurred particularly in the lungs, the skeleton and locally; low iodine uptake, particularly in distant metastases from papillary carcinomas, often made it impossible to reach a diagnosis by using radio-iodine. Some pulmonary metastases could only be demonstrated radiologically and some skeletal metastases could be shown radiologically or scintigraphically. A modified follow-up program for differentiated carcinomas is suggested, based on the highly sensitive and specific thyroglobulin determination under TSH suppression (sensitivity 97.9%, specificity 93.6%). |
| Databáze: | OpenAIRE |
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