An infrared study of the tautomerism of chlorinated 2-pyridinols isolated in an argon matrix

Autor:	Stanley S. T. King, Nancy B. Tefertiller, Wendell L. Dilling
Rok vydání:	1972
Předmět:	Argon Chemistry Infrared Organic Chemistry Infrared spectroscopy chemistry.chemical_element Ring (chemistry) Photochemistry Biochemistry Medicinal chemistry Tautomer Enol Matrix (chemical analysis) chemistry.chemical_compound Drug Discovery Pyridine
Zdroj:	Tetrahedron. 28:5859-5863
ISSN:	0040-4020
DOI:	10.1016/0040-4020(72)88118-3
Popis:	The infrared spectra of 3-, 4-, 5- and 6-monochloro-, 3,5,6-trichloro-2-pyridinols (pyridones), and of the unsubstituted 2-pyridinol isolated in a low temperature (20°K) argon matrix were studied. The results indicate that the enol/keto ratio for the isolated pyridinols decreases according to the position of the chlorine atom(s) on the pyridine ring; i.e., 3,5,6-trichloro >-6 > 5 > 4 > 3 monochloro-2-pyridinols. 3,5,6-Trichloro-2-pyridinol exists predominantly in the enol form.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::72e0a9ad399200f2b908311afc38c32a https://doi.org/10.1016/0040-4020(72)88118-3 Zobrazit plný text záznamu