Anti-Biofilm Activity of Cell-Free Supernatant of Saccharomyces cerevisiae against Staphylococcus aureus
| Autor: | Yeong Jin Park, Hyun-Dong Paik, Yeon Jin Kim, Na-Kyoung Lee, Hwan Hee Yu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
0106 biological sciences biology Chemistry Microorganism Saccharomyces cerevisiae Biofilm virus diseases General Medicine biochemical phenomena metabolism and nutrition Grapefruit seed extract medicine.disease_cause biology.organism_classification Antimicrobial 01 natural sciences Applied Microbiology and Biotechnology nervous system diseases Microbiology Cell free supernatant Staphylococcus aureus 010608 biotechnology Gene expression medicine Biotechnology |
| Zdroj: | Journal of Microbiology and Biotechnology. 30:1854-1861 |
| ISSN: | 1738-8872 1017-7825 |
| Popis: | Staphylococcus aureus is one of the most common microorganisms and causes foodborne diseases. In particular, biofilm-forming S. aureus is more resistant to antimicrobial agents and sanitizing treatments than planktonic cells. Therefore, this study aimed to investigate the anti-biofilm effects of cell-free supernatant (CFS) of Saccharomyces cerevisiae isolated from cucumber jangajji compared to grapefruit seed extract (GSE). CFS and GSE inhibited and degraded S. aureus biofilms. The adhesion ability, auto-aggregation, and exopolysaccharide production of CFS-treated S. aureus, compared to those of the control, were significantly decreased. Moreover, biofilm-related gene expression was altered upon CFS treatment. Scanning electron microscopy images confirmed that CFS exerted anti-biofilm effects against S. aureus. Therefore, these results suggest that S. cerevisiae CFS has anti-biofilm potential against S. aureus strains. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|