Abstract W P186: Elevated Brain Natriuretic Peptide Is An Independent Marker For Cardioembolism And Poor Outcome In Acute Ischemic Stroke

Autor:	Jaydip R Chaudhuri, Rukmini K Mridula, Banda Balaraju, Srinivasarao V Bandaru, Vijay K Sharma
Rok vydání:	2015
Předmět:	Advanced and Specialized Nursing cardiovascular diseases Neurology (clinical) Cardiology and Cardiovascular Medicine
Zdroj:	Stroke. 46
ISSN:	1524-4628 0039-2499
Popis:	Background: Brain natriuretic peptide (BNP) is believed to be a diagnostic marker for cardiovascular diseases, including atrial fibrillation (AF). Recent studies have incriminated BNP as a marker of cardioembolic stroke. We aimed at investigating association of plasma BNP levels in acute ischemic stroke subtypes and their outcome in Indian patients. Methods: We recruited 270 acute ischemic stroke patients within 48 hours of symptom onset and compared with 110 age and sex matched control subjects. This study was carried out at Yashoda Hospital, Hyderabad, India between April 2011 and March 2013. Serum BNP levels were estimated in stroke patients and control subjects. Good functional outcome at 3-months was defined as modified Rankin score (mRS) ≤2. Results: Elevated BNP levels was significantly more in patients with acute ischemic stroke patients 119 (44%) compared to controls 4 (3.6%) (p Conclusions: Elevated BNP level is an independent marker for cardioembolic stroke and poor outcome at 90 days follow-up. No significant association was seen with other stroke subtypes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::72b5abfed78b83b310b6c419414c093b https://doi.org/10.1161/str.46.suppl_1.wp186 Zobrazit plný text záznamu