In vivo evaluation on Malaysian coastal isolates of Gracilaria changii and Stichopus badionotus through heat-burn methicillin-resistant Staphylococcus aureus (MRSA) infection animal model
| Autor: | S. Zamberi, Vasantha Kumari Neela, M A Norfarrah, K A N I Nik, N. S. Mariana |
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| Rok vydání: | 2011 |
| Předmět: |
biology
Plant Science biochemical phenomena metabolism and nutrition MRSA infection bacterial infections and mycoses biology.organism_classification medicine.disease_cause Microbiology Methicillin-resistant Staphylococcus aureus Sea cucumber Infectious Diseases In vivo medicine Vancomycin Gracilaria changii Stichopus Staphylococcus medicine.drug |
| Zdroj: | African Journal of Microbiology Research. 5 |
| ISSN: | 1996-0808 |
| DOI: | 10.5897/ajmr10.348 |
| Popis: | Staphylococcus aureus commonly causes bacterial infections such as boils, carbuncles, infections wounds, deep abscesses and bloodstream infections (or bacteraemia). Nowadays, it becomes more difficult to treat such infections due to the appearance of resistant strain known as methicillin-resistant Staphylococcus aureus(MRSA). The objective of this study was to screen on methanolic extracts of seaweed (Gracilaria changii) and local sea cucumber (Stichopus badionotus) for their anti-MRSA activities in vitro and in vivo; by a heat-burn, wound-healing model in rats. Both extracts demonstrated in vitro anti-MRSA activity. The sea cucumber extract demonstrated the same extent of wound healing as did vancomycin at P |
| Databáze: | OpenAIRE |
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