Role of Inhaled Methoxyflurane in the Management of Acute Trauma Pain
| Autor: | Alberto Farina, Frank Coffey, Sergio Garcia Collado, Umberto Restelli, Giovanni Sbrana, Andrea Fabbri, Germana Ruggiano, Franco Marinangeli, Agnès Ricard-Hibon |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Moderate to severe
medicine.medical_specialty business.industry Inhaler Analgesic Emergency treatment Clinical trial 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine 030202 anesthesiology Methoxyflurane medicine Effective treatment Acute trauma Intensive care medicine business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of Pain Research. 13:1547-1555 |
| ISSN: | 1178-7090 |
| DOI: | 10.2147/jpr.s252222 |
| Popis: | Adequate treatment of trauma pain is an integral part of the management of trauma patients, not just for ethical reasons but also because undertreated pain can lead to increased morbidities and worse long-term outcomes. Trauma pain management presents challenges in the pre-hospital setting, particularly in adverse or hostile environments as well as in busy emergency departments (EDs). Inhaled methoxyflurane, administered at analgesic doses via a disposable inhaler, has recently become available in Europe for the emergency treatment of moderate to severe pain in conscious adult trauma patients. A growing body of evidence demonstrates that inhaled methoxyflurane is well tolerated and effective in providing a rapid onset of analgesia. In this paper, we discuss the rationale for methoxyflurane use in trauma pain management, data from clinical trials recently conducted in Europe, its efficacy and safety profile compared to current standard treatments, its place in therapy and organizational impact. We conclude that inhaled methoxyflurane represents an effective treatment option in the different settings where trauma patients require rapid and flexible pain resolution, with potential organizational advantages. |
| Databáze: | OpenAIRE |
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