Prostate Specific Antigen and Prostate Volume; How They are Correlated in Patients with Benign Prostatic Hyperplasia

Autor: Nafea Sami Enad Al-Esawi, Ehab Jasim Mohammad, Duraid Taha Abdulkareem, Waleed Nassar Jaffal, Muhammad Hammad Jasim Alajeely
Rok vydání: 2020
Předmět:
Zdroj: Medico-Legal Update.
ISSN: 0974-1283
0971-720X
DOI: 10.37506/mlu.v20i2.1210
Popis: Background: Human prostate-specific antigen (PSA) is a glycoprotein with approximately 7% (wt/wt)carbohydrate. The PSA assay, along with other diagnostic parameters, is considered the most useful earlymalignancy marker to confirm the diagnosis of prostate disease. Benign prostatic hyperplasia (BPH) andprostatic cancer are the most common prostate diseases.Objecive: The study was designed to assess the diagnostic sensitivity of PSA with different prostate volume(PV) in Iraqi men aged (40 to 88) to define better predictions for early detection of prostatic cancer.Method: The subjects involved in this study were 119 consecutive male aged (40-88) years with BPH.Prostate volume (PV) (measured by transrectal ultrasound: TRUS) and PSA density (PD) data distributionwere evaluated. Variables of the clinical and laboratory display were expressed as mean ± SD. ANOVA wereused for the comparison of variables. Pearson correlation coefficients were calculated for the whole study.Result: Mean (± SD) age of the subjects included in this study was 63.23±11.12 years (p
Databáze: OpenAIRE