IMMUNOHISTOCHEMICAL EVALUATION OF ESTROGENRECEPTOR AND PROGESTERONE RECEPTOR IN UTERINESMOOTH MUSCLE CELLTUMORS
| Autor: | Pooja Jain, Vivek Singh, Ashutosh Kumar, Ankita Mittal, Shubhra Agrawal, Seema Awasthi, Faiyaz Ahmad |
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| Rok vydání: | 2023 |
| Předmět: |
Cultural Studies
Pulmonary and Respiratory Medicine History Visual Arts and Performing Arts General Chemical Engineering Strategy and Management General Mathematics General Chemistry Cell Biology Education Cellular and Molecular Neuroscience Philosophy Geophysics Geochemistry and Petrology General Earth and Planetary Sciences Cardiology and Cardiovascular Medicine Law Molecular Biology Social Sciences (miscellaneous) Music General Environmental Science |
| Zdroj: | PARIPEX INDIAN JOURNAL OF RESEARCH. :133-135 |
| DOI: | 10.36106/paripex/1410532 |
| Popis: | Objective: To study the histo-morphological spectrum of uterine smooth cell tumors withimmunohistochemical expression of estrogen and progesterone receptor and to compare theirexpression with respect to that of surrounding myometrium. Materials & Methods: The study is conducted at a tertiary care hospital in northern India which included themyomectomy as well as hysterectomy specimens of the smooth muscle cell tumor. This study found th Results: at the majority of leiomyoma tumors express positivity for estrogen and progesterone receptors, with one-third showing moderate expression and the rest showing strong expression. The study concludes that the majority of Conclusion: uterine smooth muscle tumors are benign and hormone receptor expression, particularly ER, may play a crucial role in their development and progression, highlighting the need for further research to improve diagnostic and treatment approaches. Additionally, a decrease in hormone receptor expression was observed as tumors progressed from benign to malignant, but the conclusion is limited due to the small number of tumors demonstrating atypical characteristics |
| Databáze: | OpenAIRE |
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