Novel preparation of (−)-4-hydroxycyclohex-2-enone: reaction of 4-hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone with some thiols

Autor:	Ben S. Morgan, Stanley M. Roberts, Paul Evans, Alastair D. Meek, Jamie F. Bickley
Rok vydání:	2006
Předmět:	Inorganic Chemistry Nitrosobenzene chemistry.chemical_compound chemistry Yield (chemistry) Organic Chemistry Organic chemistry Physical and Theoretical Chemistry Enone Catalysis
Zdroj:	Tetrahedron: Asymmetry. 17:355-362
ISSN:	0957-4166
DOI:	10.1016/j.tetasy.2006.01.002
Popis:	A new route to ( R )-4-hydroxycyclohex-2-enone from cyclohexanedione monoketal (27% yield) commences with reaction of the ketal with nitrosobenzene catalysed by l -proline. 4-Hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone react with thiols to afford the corresponding syn -disubstituted cycloalkanones.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::7276c4b0dcff8c3e531b2c3787772650 https://doi.org/10.1016/j.tetasy.2006.01.002 Zobrazit plný text záznamu Full Text from ScienceDirect