Caffeic acid derivatives as growth inhibitors of Setaria viridis: Structure-activity relationships and mechanisms
| Autor: | Xia Ren, Kai Guo, Le Pan, Min Xie, Xiuzhuang Li, Hui Jin, Zhiqiang Yan, Bo Qin, Xiao-Feng He, Jun-de Liu, Xiaoyan Yang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0106 biological sciences
0301 basic medicine Stereochemistry Plant Science 01 natural sciences Biochemistry Cinnamic acid 03 medical and health sciences chemistry.chemical_compound Caffeic acid Allelopathy biology Setaria viridis food and beverages biology.organism_classification 030104 developmental biology chemistry Catalase biology.protein Phytotoxicity Growth inhibition Agronomy and Crop Science Lead compound 010606 plant biology & botany Biotechnology |
| Zdroj: | Phytochemistry Letters. 20:208-213 |
| ISSN: | 1874-3900 |
| DOI: | 10.1016/j.phytol.2017.04.041 |
| Popis: | Weeds bring severe threats to agricultural production and most traditional herbicides cause serious pollution to the environment. Caffeic acid is a potential allelochemical of many crops. To develop novel herbicides, a series of trans -caffeic acid analogues were prepared to evaluate their growth inhibition on S. viridis and investigate structure-activity relationships. Presence of hydroxyl groups on the benzene ring greatly reduced the phytotoxicity of analogues and the double bond seemed not to be necessary. Moreover, it was found that halogenated cinnamic acid analogues showed potent inhibitory activity. 4-Fluorocinnamic acid (4-FCA) displayed the strongest growth inhibition in a concentration-dependent manner, whereas it induced significantly weaker inhibition on wheat. This selectivity could help us to develop a novel herbicide. Exposure of S. viridis to 4-FCA increased levels of H 2 O 2 and catalase (CAT) in roots, suggesting that the inhibitory effect of 4-FCA might be related to oxidative stress. Thus, we have found an active lead compound for a novel herbicide derived from crop allelochemicals, which may help in the development of new environmentally safe herbicides. |
| Databáze: | OpenAIRE |
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