A New Sexangularetin Derivative From Camellia hakodae
| Autor: | Tran Van Hieu, Pham G. Dien, Tran Ninh, Vu Dinh Hoang, Nguyen Thanh Hung, Nguyen T. Tuyen |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pharmacology
chemistry.chemical_classification Sexangularetin 010405 organic chemistry Stereochemistry Flavonoid Plant Science General Medicine 01 natural sciences 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Complementary and alternative medicine chemistry Drug Discovery Camellia Derivative (chemistry) |
| Zdroj: | Natural Product Communications. 14:1934578X1987620 |
| ISSN: | 1555-9475 1934-578X |
| DOI: | 10.1177/1934578x19876209 |
| Popis: | A new flavonoid, sexangularetin 3- O-(2″- O-( E) -p-coumaroyl-β -d-glucopyranoside) (1), together with 9 known flavonoid compounds (2-10), was isolated from flowers of Camellia hakodae Ninh. Their structures were established based on physicochemical and spectroscopic analyses. The new compound displayed moderate to weak cytotoxic activities against HepG2 (IC50 192.0 μg/mL), Lu (IC50 90.2 μg/mL), and KB (IC50 72.7 μg/mL) cell lines, and inactivity against MCF7 (IC50 256.0 μg/mL). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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