Conformational changes induced in α-elastin by cholesterol, taurocholate and unsaturated fatty acids

Autor: A.M. Tamburro, D. Daga Gordini, Valeria Guantieri
Rok vydání: 1980
Předmět:
Zdroj: International Journal of Biological Macromolecules. 2:68-72
ISSN: 0141-8130
DOI: 10.1016/0141-8130(80)90030-6
Popis: The ability of sodium taurocholate, cholesterol and oleic, linoleic and palmitoleic acids to induce conformational changes in α-elastin has been studied by circular dichroism. In addition, the influence of Ca 2+ ions has been investigated. The formation of inelastic structure (α-helix, β-form) in the protein has been evidenced by spectral data. These results could be of interest in relation to aging and atherogenesis.
Databáze: OpenAIRE