QM/MM Study of the Reaction Mechanism of the Dehydratase Domain from Mammalian Fatty Acid Synthase
| Autor: | Rui P. P. Neves, Fabiola E. Medina, Pedro A. Fernandes, Maria J. Ramos |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Reaction mechanism biology 010405 organic chemistry General Chemistry 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences QM/MM chemistry.chemical_compound Fatty acid synthase Enzyme chemistry Biochemistry Biosynthesis Dehydratase biology.protein |
| Zdroj: | ACS Catalysis. 8:10267-10278 |
| ISSN: | 2155-5435 |
| DOI: | 10.1021/acscatal.8b02616 |
| Popis: | Dehydratase (DH) is a catalytic domain of the mammalian fatty acid synthase (mFAS), a multidomain enzyme with seven different active sites that work in tandem to carry out the biosynthesis of palmi... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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