In Vivo Activation of Mouse Macrophages with β-l,3-D-Glucan-Derivatized Plastic Beads

Autor: J. Bøgwald, Olle Larm, Rolf Seljelid, L. T. Rasmussen, James Hoffman, J. Ugelstad, A. Berge
Rok vydání: 2006
Předmět:
Zdroj: Scandinavian Journal of Immunology. 21:601-605
ISSN: 0300-9475
DOI: 10.1111/j.1365-3083.1985.tb01850.x
Popis: Macrophages obtained from animals treated with beta-1,3-D-glucan-derivatized plastic beads were greatly stimulated, as judged by morphology, esterase release, and cytostatic effect on L-929 tumour cells in vitro. The pretreatment of mice with such beads conferred an apparent absolute local resistance to an otherwise lethal pneumococcal infection but had no effect on the growth of intraperitoneal AA ascites sarcoma. Moreover, peritoneal cells from animals pretreated with glucan beads did not protect the animals in a Winn assay.
Databáze: OpenAIRE