Flash vacuum pyrolysis (F.V.P.) of 1,2,4-benzotriazine derivatives

Autor:	Walter José Peláez, György Hajós, Gloria I. Yranzo, Zsuzsanna Riedl, Elizabeth L. Moyano, Ioulia T. Gafarova
Rok vydání:	2003
Předmět:	chemistry.chemical_compound Benzimidazole Benzonitrile chemistry Flash vacuum pyrolysis Radical Organic Chemistry Drug Discovery Organic chemistry Biphenylene Biochemistry Medicinal chemistry Deoxygenation
Zdroj:	Tetrahedron. 59:851-856
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(02)01598-3
Popis:	Flash vacuum pyrolysis of 3-methylsulfanyl-1,2,4-benzotriazine N-oxide, 3-methylsulfanyl-1,2,4-benzotriazine, and 3-phenyl-1,2,4-benzotriazine are described. The N-oxide derivative underwent deoxygenation between 500 and 600°C, whereas at higher temperatures both methylsulfanyl compounds, besides yielding the same products, also gave benzimidazole formed by an independent mechanism. Transformation of these derivatives between 600 and 750°C led to formation of a complex reaction mixture indicating the radical nature of the processes. The phenyl substituted derivative was studied between 575 and 650°C and afforded benzonitrile and traces of biphenylene.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::71fbff04e6fe85d1b8ba1aafa28bee46 https://doi.org/10.1016/s0040-4020(02)01598-3 Zobrazit plný text záznamu Full Text from ScienceDirect