Gingival health status in renal transplant recipients: relationship between systemic inflammation and atherosclerosis

Autor: Alper Kirkpantur, Bulent Altun, Murat Ozbek, Nihal Avcu, Cetin Turgan, Özden Kansu, Ünal Yasavul, Rahmi Yilmaz, Mehmet Bakkaloglu, Serkan Kahraman, Yunus Erdem, Gultekin Genctoy, Mustafa Arici, Hilmi Kansu
Rok vydání: 2007
Předmět:
Zdroj: International Journal of Clinical Practice. 61:577-582
ISSN: 1368-5031
DOI: 10.1111/j.1742-1241.2007.01283.x
Popis: Summary Cardiovascular disease (CVD) is the leading cause of mortality in renal transplant recipients (RTR). Systemic and periodontal inflammation has been suggested to have a possible role in the development of atherosclerosis. In the present study, we aimed to investigate the relationship between gingival health status, inflammation and atherosclerosis in RTRs. Eighty-three RTR (50 male, 33 female) were enrolled in the study. Routine biochemical analyses, serum lipoproteins, C-reactive protein, fibrinogen, homocystein, parathyroid hormone (PTH) and cyclosporin A (CsA) trough levels were studied. All patients had 24-h ambulatory blood pressure monitoring and B-mode ultrasound of the common carotid arteries. Gingival status was evaluated by the Loe and Silness gingival index (GI). Mean GI value was 2.3 ± 0.5. Fifty patients (60.3%) had GI value ≥ 2.1 (severe gingivitis; group A). Thirty-three patients (39.7%) had GI value
Databáze: OpenAIRE