Effect of Citrullus vulgaris on some functional indices of selected tissues of Wistar rats

Autor: Johnson Oe, Oluwakemi Josephine Awakan, Awakan Va, Oloyede O, Oluyomi Stephen Adeyemi
Rok vydání: 2016
Předmět:
Zdroj: Comparative Clinical Pathology. 25:1127-1132
ISSN: 1618-565X
1618-5641
Popis: Citrullus vulgaris (watermelon) is a fruit with prophylactic and therapeutic potentials. In an attempt to maximize these potentials, the seed and rind are now often consumed together with the pulp. This study aimed at evaluating the implications of such consumption. Study involved the use of 35 Wistar rats grouped into seven with a control group administered distilled water, and the other groups administered varying concentrations of the pulp and whole fruit for 28 days. Alanine and aspartate aminotransferase (ALT, AST) were assayed in the serum and liver. Total protein of the serum and selected tissues was determined and malondialdehyde (MDA) level measured. Phytochemical screening revealed the presence of steroids, saponin, alkaloids, flavonoids, and terpenoids in both whole fruit and pulp. Significant increases (p
Databáze: OpenAIRE