Myocardial Function and Metabolism in Shock: The Effect of an ?Elemental? Diet

Autor: W. D. Fisher, I. McA. Ledingham, C. S. Mcardle, M. Maddern
Rok vydání: 1975
Předmět:
Zdroj: European Journal of Intensive Care Medicine. 1:3-9
ISSN: 1432-1238
0340-0964
DOI: 10.1007/bf00735863
Popis: The extent to which cardiac failure contributes to death following experimental canine haemorrhagic shock remains uncertain. However, previous studies suggested the presence of a myocardial metabolic defect in that, after prolonged haemorrhagic shock, myocardial oxygen consumption did not recover with transfusion. Massive intestinal blood loss complicated interpretation of the haemodynamic pattern during the phase of resuscitation. In the present study, the use of a special “elemental” diet was shown to eliminate the intestinal blood loss and the need for supplimentary blood transfusion. Nonetheless, the diminished myocardial oxygen consumption after retransfusion persisted. Possible explanations for this finding include myocardial ischaemia, metabolic acidosis and the presence of extracardiac circulating myocardial depressant substances.
Databáze: OpenAIRE