CHANGES IN THE ARTERIES OF THE UTERUS IN OÖPHORECTOMIZED RATS

Autor: Thomas C. Laipply, Joseph R. Kahn
Rok vydání: 1941
Předmět:
Zdroj: Endocrinology. 29:1017-1019
ISSN: 1945-7170
0013-7227
Popis: IT WAS SHOWN BY LANGSTON and Robinson (i) in the rat and by Buys and Vandervelde (2) in the rabbit that after bilateral oophorectomy the uterus becomes atrophic, the walls of uterine blood vessels increase in thickness and their lumen decrease in size. It is well known that in women after the menopause, especially multipara, many of the blood vessels of the uterus show marked thickening and hyalinization of the intima and great narrowing of the lumen. The purpose of this study was to determine whether atrophy which is not due to direct interference with the blood supply of an organ will induce the development of intimal arterial and arteriolar sclerosis of the blood vessels of that organ. The ovaries were removed from 50 middle-aged rats. Biopsies were taken from the uterine horns at the time of oophorectomy as control tissue.
Databáze: OpenAIRE