70 O - Prognostic pactors in acute leukemias

Autor: E. Karaagaoglu, E. Ozyilkan, S. Ariogul
Rok vydání: 1996
Předmět:
Zdroj: European Journal of Cancer. 32:S14
ISSN: 0959-8049
DOI: 10.1016/0959-8049(96)84824-6
Popis: Pretreatment prognostic factors were evaluated in 173 patients with acute myeloid leukemia (AML) and 78 patients with acute lymphoblastic leukemia (ALL) followed between 1980 and 1990. The effects of factors to survival were analyzed by log-rank test. In AML cases, patients between 17–31 year age, who were symptomatic for less than 2 months, with blast cells less than 602 in peripheral blood shear, without infection, followed between 1985–1990 lived longer (p( Factors that may be important in CR were evaluated by multivariate regression analyses. In AML cases, age, follow up period, white blood cell count (WBC), and symptoms duration were found important in achieving CR (p = 0.006, p = 0.049, P = 0.0171, and p = 0.212, respectively). In ALL cases, age, follow up period, Blast Percent in peripheral blood smear, WBC and platelet count were found important for CR (p = 0.021, p = 0.038, p = 0.072, p = 0.150 and p = 0.192, respectively). In conclusions, we decided that some pretreatment factors were important both in survival and CR in acute leukemia patients.
Databáze: OpenAIRE