Analysis and Pharmacokinetics of Apomorphine in Rat Brain by Microdialysis Coupled with Microbore HPLC Electrochemical Detection

Autor: K. W. Kuo, T. R. Tsai, Tung Hu Tsai, Chieh Fu Chen, Fu-Chou Cheng
Rok vydání: 1997
Předmět:
Zdroj: Journal of Liquid Chromatography & Related Technologies. 20:481-490
ISSN: 1520-572X
1082-6076
Popis: The feasibility of an on-line microdialysis coupled with a sensitive microbore high performance liquid chromatography with electrochemical detection (HPLC-ED) system for the direct analysis of apomorphine was investigated. A microdialysis probe was inserted into the right striatum of male Sprague-Dawley rats, which had been administered apomorphine (10 mg/kg, i.v.).
Databáze: OpenAIRE