Analysis and Pharmacokinetics of Apomorphine in Rat Brain by Microdialysis Coupled with Microbore HPLC Electrochemical Detection
Autor: | K. W. Kuo, T. R. Tsai, Tung Hu Tsai, Chieh Fu Chen, Fu-Chou Cheng |
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Rok vydání: | 1997 |
Předmět: | |
Zdroj: | Journal of Liquid Chromatography & Related Technologies. 20:481-490 |
ISSN: | 1520-572X 1082-6076 |
Popis: | The feasibility of an on-line microdialysis coupled with a sensitive microbore high performance liquid chromatography with electrochemical detection (HPLC-ED) system for the direct analysis of apomorphine was investigated. A microdialysis probe was inserted into the right striatum of male Sprague-Dawley rats, which had been administered apomorphine (10 mg/kg, i.v.). |
Databáze: | OpenAIRE |
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