Development and Execution of a Production-Scale Continuous [2 + 2] Photocycloaddition

Autor: Wang Bin, Siân C. Jones, Lu Jiangping, Song-yuan Zheng, Jian Tao, Jason S. Tedrow, Miguel Gonzalez, Matthew G. Beaver, Zhi-qing Liu, Zhang Enxuan
Rok vydání: 2020
Předmět:
Zdroj: Organic Process Research & Development. 24:2139-2146
ISSN: 1520-586X
1083-6160
DOI: 10.1021/acs.oprd.0c00185
Popis: This article details the approach to large-scale production of cyclobutane 2 by the continuous-flow [2 + 2] photocycloaddition of maleic anhydride and ethylene, including (1) focused reaction optim...
Databáze: OpenAIRE