A Facile Synthesis of Trifluoromethylamines by Oxidative Desulfurization–Fluorination of Dithiocarbamates

Autor:	Tamejiro Hiyama, Kiyoshi Kanie, Katsuya Mizuno, Manabu Kuroboshi
Rok vydání:	1998
Předmět:	chemistry.chemical_compound chemistry Trifluoromethylation Reagent Polymer chemistry Halogen Organic chemistry General Chemistry Oxidative phosphorylation Imide Flue-gas desulfurization
Zdroj:	Bulletin of the Chemical Society of Japan. 71:1973-1991
ISSN:	1348-0634 0009-2673
DOI:	10.1246/bcsj.71.1973
Popis:	Trifluoromethylamines are easily synthesized from dithiocarbamates by a reagent system consisting of tetrabutylammonium dihydrogentrifluoride and an N-halo imide under mild conditions. When this reaction was applied to dithiocarbamates ArN(R)CS2Me at higher temperatures, the trifluoromethylation was accompanied by halogen substitution at the p-position of the Ar group. The synthesis of trifluoromethyl-substituted adenosine is also described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::719bef42baea9b348c226a0bb670c0dc https://doi.org/10.1246/bcsj.71.1973 Zobrazit plný text záznamu