Homoarginine Oligomers as Trypsin and Chymotrypsin Substrates and Inhibitors

Autor:	Y. Elkana, N. Segal, L. Schwartz, M. Rigbi, D. Kliger
Rok vydání:	1974
Předmět:	chemistry.chemical_classification Chymotrypsin biology Kunitz STI protease inhibitor Stereochemistry Cleavage (embryo) Trypsin Amino acid chemistry.chemical_compound chemistry Amide biology.protein medicine Peptide bond Lithium chloride medicine.drug
Zdroj:	Bayer-Symposium ISBN: 9783642879685
Popis:	The object of this work was to obtain synthetic, reversible trypsin inhibitors. The work is based on a consideration of the length of the positively-charged amino acid side-chain which makes its ester, amide or peptide bond most susceptible to cleavage by trypsin. It is well-known that between the positively-charged atom and the α-carbon, four atoms are optimal.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::71976c357a9bfb4605800599a23bb1f3 https://doi.org/10.1007/978-3-642-87966-1_59 Zobrazit plný text záznamu