Croton zambesicus Root Extract Exert Laxative Effect in Rats

Autor: Emmanuel E. Nyong, Augustine Bassey, Utibe A. Edem, Jude E. Okokon
Rok vydání: 2020
Předmět:
Zdroj: Asian Journal of Biology. :22-26
ISSN: 2456-7124
DOI: 10.9734/ajob/2020/v10i230103
Popis: Background: Croton zambesicus Muell Arg. (Euphorbiaceace) is a medicinal plant used traditionally in the treatment of some ailments. Aim: The root extract of Croton zambesicus was evaluated for effect on the gastrointestinal tract (GIT). Materials and Methods: The root extract of C. zambesicus (27-81 mg/kg) was investigated for laxative effect in rats using different experimental models to study its effect on the GIT. Results: The extract was found to significantly increase the frequency and output of faecal matters in rats in all the experimental models studied. Conclusion: The findings of this study show that the root extract of C. zambesicus has a significant laxative effect and this supports its use in ethnomedicine for the treatment of gastrointestinal tract disorders.
Databáze: OpenAIRE