REnal Flow and Microstructure AnisotroPy (REFMAP) MRI in Normal and Peritumoral Renal Tissue
| Autor: | James S. Babb, James S. Wysock, Thorsten Feiweier, Artem Mikheev, David R. Stoffel, Andrea L. Liu, William C. Huang, Henry Rusinek, Eric E. Sigmund, Hersh Chandarana |
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| Rok vydání: | 2018 |
| Předmět: |
Reproducibility
Kidney Medullary cavity Intraclass correlation business.industry 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Fractional anisotropy medicine Radiology Nuclear Medicine and imaging Stage (cooking) Nuclear medicine business Intravoxel incoherent motion Diffusion MRI |
| Zdroj: | Journal of Magnetic Resonance Imaging. 48:188-197 |
| ISSN: | 1053-1807 |
| Popis: | BACKGROUND Diffusion-weighted imaging (DWI) provides insight into the pathophysiology underlying renal dysfunction. Variants of DWI include intravoxel incoherent motion (IVIM), which differentiates between microstructural diffusion and vascular or tubular flow, and diffusion tensor imaging (DTI), which quantifies diffusion directionality. PURPOSE To investigate the reproducibility of joint IVIM-DTI and compare controls to presurgical renal mass patients. STUDY TYPE Prospective cross-sectional. SUBJECTS Thirteen healthy controls and ten presurgical renal mass patients were scanned. Ten controls were scanned twice to investigate reproducibility. FIELD STRENGTH/SEQUENCE Subjects were scanned on a 3T system using 10 b-values and 20 diffusion directions for IVIM-DTI in a study approved by the local Institutional Review Board. ASSESSMENT Retrospective coregistration and measurement of joint IVIM-DTI parameters were performed. STATISTICAL ANALYSIS Parameter reproducibility was defined as intraclass correlation coefficient (ICC) >0.7 and coefficient of variation (CV) |
| Databáze: | OpenAIRE |
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