Vulvar Squamous Cell Carcinoma in a Patient with AIDS: A Case Study
| Autor: | Parinaz Ayat, Sarah A. Goldman, Arkadij Grigorian, Sara Sharif, Kevin Hewitt, Isabel M. McFarlane |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
integumentary system urogenital system Vulvar Squamous Cell Carcinoma business.industry Precursor lesion HPV infection Clinical course Disease Vulvar cancer medicine.disease Vulvar intraepithelial neoplasia Dermatology female genital diseases and pregnancy complications Acquired immunodeficiency syndrome (AIDS) medicine General Earth and Planetary Sciences business General Environmental Science |
| Zdroj: | American Journal of Medical Case Reports. 8:522-527 |
| ISSN: | 2374-2151 |
| DOI: | 10.12691/ajmcr-8-12-25 |
| Popis: | Vulvar cancer comprises 5% of gynecological cancers with squamous cell carcinoma (SCC) being found in 90% of the cases. Vulvar intraepithelial neoplasia is human papilloma virus (HPV)-driven and is the precursor lesion in nearly 40% of all cases of vulvar SCC. Pruritus is reported as the most common initial manifestation of vulvar SCC which may be of a long duration with pain, discharge, and bleeding been less frequently reported which contributes to the delayed initial presentation of the disease. So far, there are no recommended screening strategies for vulvar cancer and HPV vaccination may be the only effective way for prevention. We present a case of advanced vulvar cancer in an immunocompromised host. We will review pertinent topics for the clinicians on HPV infection prevention, clinical course, staging and the need for strong efforts on patient education. |
| Databáze: | OpenAIRE |
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