Oxatomide in the Treatment of Chronic Urticaria

Autor:	R. L. J. Mertens, J. Morias, W. Peremans, H. Campaert
Rok vydání:	1981
Předmět:	medicine.medical_specialty Allergy Erythema business.industry Placebo-controlled study Dermatology medicine.disease Placebo Double blind Internal medicine medicine Itching Oxatomide medicine.symptom business Chronic urticaria medicine.drug
Zdroj:	Dermatology. 162:42-50
ISSN:	1421-9832 1018-8665
DOI:	10.1159/000250232
Popis:	Oxatomide was evaluated in a double-blind study of 35 patients with chronic urticaria. For 5 weeks patients received at random either 30 mg oxatomide b.i.d. or a placebo. Oxatomide significantly reduced not only the duration of the attacks but also the severity of erythema, lesions and itching. This lower level of suffering was clearly reflected by a diminished need for additional antiallergic medication. The overall response to treatment was rated excellent or good in 72% of the oxatomide-treated patients against only 23% of the controls which is a significant difference. Sleepiness was reported in 1 patient of each group.
Databáze:	OpenAIRE
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